Found 7 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Tyrosine-protein kinase JAK2
(Homo sapiens (Human)) | BDBM47429
(7-chloranyl-1,3,6-trimethyl-pteridine-2,4-dione | ...)Show InChI InChI=1S/C9H9ClN4O2/c1-4-6(10)12-7-5(11-4)8(15)14(3)9(16)13(7)2/h1-3H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
PC cid PC sid UniChem
| PCBioAssay
| n/a | n/a | 4.56E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute Molecular Screening Center
Curated by PubChem BioAssay
| Assay Description Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institute (TS... |
PubChem Bioassay (2009)
BindingDB Entry DOI: 10.7270/Q20863Q9 |
More data for this Ligand-Target Pair | |
Receptor-interacting serine/threonine-protein kinase 2
(Homo sapiens (Human)) | BDBM47429
(7-chloranyl-1,3,6-trimethyl-pteridine-2,4-dione | ...)Show InChI InChI=1S/C9H9ClN4O2/c1-4-6(10)12-7-5(11-4)8(15)14(3)9(16)13(7)2/h1-3H3 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| Purchase
PC cid PC sid UniChem
| PCBioAssay
| n/a | n/a | 4.73E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute Molecular Screening Center
Curated by PubChem BioAssay
| |
PubChem Bioassay (2012)
BindingDB Entry DOI: 10.7270/Q2T15278 |
More data for this Ligand-Target Pair | |
DNA damage-inducible transcript 3 protein
(Mus musculus) | BDBM47429
(7-chloranyl-1,3,6-trimethyl-pteridine-2,4-dione | ...)Show InChI InChI=1S/C9H9ClN4O2/c1-4-6(10)12-7-5(11-4)8(15)14(3)9(16)13(7)2/h1-3H3 | KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
PC cid PC sid UniChem
| PCBioAssay
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Emory University Molecular Libraries Screening Center
Curated by PubChem BioAssay
| Assay Description NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Dr. Randal Kaufman, Univer... |
PubChem Bioassay (2010)
BindingDB Entry DOI: 10.7270/Q2PC30VZ |
More data for this Ligand-Target Pair | |
X-box-binding protein 1
(Homo sapiens (Human)) | BDBM47429
(7-chloranyl-1,3,6-trimethyl-pteridine-2,4-dione | ...)Show InChI InChI=1S/C9H9ClN4O2/c1-4-6(10)12-7-5(11-4)8(15)14(3)9(16)13(7)2/h1-3H3 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| Purchase
PC cid PC sid UniChem
| PCBioAssay
| n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Emory University Molecular Libraries Screening Center
Curated by PubChem BioAssay
| Assay Description NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Dr. Randal Kaufman, Univer... |
PubChem Bioassay (2011)
BindingDB Entry DOI: 10.7270/Q2NK3CGB |
More data for this Ligand-Target Pair | |
DNA damage-inducible transcript 3 protein
(Mus musculus) | BDBM47429
(7-chloranyl-1,3,6-trimethyl-pteridine-2,4-dione | ...)Show InChI InChI=1S/C9H9ClN4O2/c1-4-6(10)12-7-5(11-4)8(15)14(3)9(16)13(7)2/h1-3H3 | KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
PC cid PC sid UniChem
| PCBioAssay
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Emory University Molecular Libraries Screening Center
Curated by PubChem BioAssay
| Assay Description NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Dr. Randal Kaufman, Univer... |
PubChem Bioassay (2011)
BindingDB Entry DOI: 10.7270/Q28C9TQN |
More data for this Ligand-Target Pair | |
Beta-lactamase
(Pseudomonas aeruginosa) | BDBM47429
(7-chloranyl-1,3,6-trimethyl-pteridine-2,4-dione | ...)Show InChI InChI=1S/C9H9ClN4O2/c1-4-6(10)12-7-5(11-4)8(15)14(3)9(16)13(7)2/h1-3H3 | PDB MMDB
KEGG
UniProtKB/TrEMBL
B.MOAD GoogleScholar AffyNet
| Purchase
PC cid PC sid UniChem
| PCBioAssay
| n/a | n/a | >4.98E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute Molecular Screening Center
Curated by PubChem BioAssay
| |
PubChem Bioassay (2012)
BindingDB Entry DOI: 10.7270/Q2XS5T0R |
More data for this Ligand-Target Pair | |
Heat shock factor protein 1
(Mus musculus) | BDBM47429
(7-chloranyl-1,3,6-trimethyl-pteridine-2,4-dione | ...)Show InChI InChI=1S/C9H9ClN4O2/c1-4-6(10)12-7-5(11-4)8(15)14(3)9(16)13(7)2/h1-3H3 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| Purchase
PC cid PC sid UniChem
| PCBioAssay
| n/a | n/a | n/a | n/a | 1.43E+4 | n/a | n/a | n/a | n/a |
Broad Institute
Curated by PubChem BioAssay
| Assay Description Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Confirmation testing of small molecules identifie... |
PubChem Bioassay (2010)
BindingDB Entry DOI: 10.7270/Q2P55KXK |
More data for this Ligand-Target Pair | |