Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 439.5 BDBM77237Purchase

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Endothelial PAS domain-containing protein 1 (Homo sapiens (Human))	BDBM77237 (3-(5,7-dimethyl-2-phenyl-6-pyrazolo[1,5-a]pyrimidi...) Show SMILES Cc1nc2cc(nn2c(C)c1CCC(=O)N1CCN(CC1)c1ccccc1)-c1ccccc1 Show InChI InChI=1S/C27H29N5O/c1-20-24(21(2)32-26(28-20)19-25(29-32)22-9-5-3-6-10-22)13-14-27(33)31-17-15-30(16-18-31)23-11-7-4-8-12-23/h3-12,19H,13-18H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	1.05E+3	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay									PubChem Bioassay (2012) BindingDB Entry DOI: 10.7270/Q2WS8RVZ
					More data for this Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H (Homo sapiens (Human))	BDBM77237 (3-(5,7-dimethyl-2-phenyl-6-pyrazolo[1,5-a]pyrimidi...) Show SMILES Cc1nc2cc(nn2c(C)c1CCC(=O)N1CCN(CC1)c1ccccc1)-c1ccccc1 Show InChI InChI=1S/C27H29N5O/c1-20-24(21(2)32-26(28-20)19-25(29-32)22-9-5-3-6-10-22)13-14-27(33)31-17-15-30(16-18-31)23-11-7-4-8-12-23/h3-12,19H,13-18H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	4.59E+3	n/a	n/a	n/a	n/a
Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters Curated by PubChem BioAssay					Assay Description Assay Provider: Xinmin Xie Assay Provider Affiliation: Bioscience Division, SRI International, Menlo Park, CA Grant Title: HTS Assay for Cav3 T-Type ...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2B856KG
					More data for this Ligand-Target Pair