Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Protein kinase C theta type
(Homo sapiens (Human)) | BDBM35164
(5-vinyl-3-pyridinecarbonitrile, 47)Show SMILES Cc1ncc(C#N)c(Nc2ccc3[nH]ccc3c2C)c1\C=C\CCN1CCNCC1 Show InChI InChI=1S/C24H28N6/c1-17-20-8-9-27-23(20)7-6-22(17)29-24-19(15-25)16-28-18(2)21(24)5-3-4-12-30-13-10-26-11-14-30/h3,5-9,16,26-27H,4,10-14H2,1-2H3,(H,28,29)/b5-3+ | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 17 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
| Assay Description
All IC50s were measured by using a modified IMAP protocol from Molecular Devices. The kinase reaction was carried out in a Corning Costar 384 well pl... |
Bioorg Med Chem 17: 7933-48 (2009)
Article DOI: 10.1016/j.bmc.2009.10.020
BindingDB Entry DOI: 10.7270/Q2M043RT |
More data for this
Ligand-Target Pair | |
Protein kinase C delta type
(Homo sapiens (Human)) | BDBM35164
(5-vinyl-3-pyridinecarbonitrile, 47)Show SMILES Cc1ncc(C#N)c(Nc2ccc3[nH]ccc3c2C)c1\C=C\CCN1CCNCC1 Show InChI InChI=1S/C24H28N6/c1-17-20-8-9-27-23(20)7-6-22(17)29-24-19(15-25)16-28-18(2)21(24)5-3-4-12-30-13-10-26-11-14-30/h3,5-9,16,26-27H,4,10-14H2,1-2H3,(H,28,29)/b5-3+ | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 120 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
| Assay Description
All IC50s were measured by using a modified IMAP protocol from Molecular Devices. The kinase reaction was carried out in a Corning Costar 384 well pl... |
Bioorg Med Chem 17: 7933-48 (2009)
Article DOI: 10.1016/j.bmc.2009.10.020
BindingDB Entry DOI: 10.7270/Q2M043RT |
More data for this
Ligand-Target Pair | |