Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 553.9 BDBM324218

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor IX (Homo sapiens (Human))	BDBM324218 (US10189819, Example 55) Show SMILES Cc1ncn(n1)-c1ccc(C(=O)NCC(c2nc3cc(C)c(C)cc3[nH]2)c2ccc(nc2)C(F)(F)F)c(Cl)c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	427	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme, Corp.; Mochida Paraceuticals Co., Ltd. US Patent					Assay Description Formation of a clot to stem bleeding at a site of blood vessel injury involves the coordinated activity of a group of plasma proteins that initiate a...				US Patent US10189819 (2019) BindingDB Entry DOI: 10.7270/Q200046Z
					More data for this Ligand-Target Pair