Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 474.3 BDBM393723

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor IX (Homo sapiens (Human))	BDBM393723 ((R)—N-(1-(3-Amino-4-chloroisoxazolo[5,4-c]pyridin-...) Show SMILES Cc1ncn(n1)-c1cnc(C(=O)N[C@@H]2CCN(C2)c2ncc(Cl)c3c(N)noc23)c(Cl)c1 |r| Show InChI InChI=1S/C19H17Cl2N9O2/c1-9-25-8-30(27-9)11-4-12(20)15(23-5-11)19(31)26-10-2-3-29(7-10)18-16-14(13(21)6-24-18)17(22)28-32-16/h4-6,8,10H,2-3,7H2,1H3,(H2,22,28)(H,26,31)/t10-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
Universita degli Studi di Roma La Sapienza					Assay Description Inhibitory activity against factor IXa was tested using the substrate SPECTROFLUOR FIXa (american diagnostica inc.; 500 West Avenue, Stamford, Conn. ...				J Med Chem 52: 2818-24 (2009) BindingDB Entry DOI: 10.7270/Q2WQ063R
					More data for this Ligand-Target Pair