Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 424.5 BDBM521092

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Muscarinic acetylcholine receptor M4 (Homo sapiens (Human))	BDBM521092 (6-(1,3-dimethylpyrazol-4-yl)-N-[[7- (tetrahydropyr...) Show SMILES Cc1nn(C)cc1-c1ccc(NCC2CC3(C2)CCN(CC2CCOCC2)CC3)nn1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...				Citation and Details BindingDB Entry DOI: 10.7270/Q2XD14VC
					More data for this Ligand-Target Pair