Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Integrin alpha-V/beta-3
(Homo sapiens (Human)) | BDBM50083771
(2-(3,5-Dimethyl-isoxazole-4-sulfonylamino)-3-({5-[...)Show SMILES Cc1noc(C)c1S(=O)(=O)N[C@@H](CNC(=O)C1=NOC(CCCCNc2ncc[nH]2)C1)C(O)=O |t:17| Show InChI InChI=1S/C19H27N7O7S/c1-11-16(12(2)32-24-11)34(30,31)26-15(18(28)29)10-23-17(27)14-9-13(33-25-14)5-3-4-6-20-19-21-7-8-22-19/h7-8,13,15,26H,3-6,9-10H2,1-2H3,(H,23,27)(H,28,29)(H2,20,21,22)/t13?,15-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 73 | n/a | n/a | n/a | n/a | n/a | n/a |
DuPont Pharmaceuticals Company
Curated by ChEMBL
| Assay Description
Inhibition of vitronectin receptor (alpha V beta 3), expressed on human 293 cells, binding to immobilized fibrinogen |
J Med Chem 43: 27-40 (2000)
BindingDB Entry DOI: 10.7270/Q2571B77 |
More data for this
Ligand-Target Pair | |
Integrin alpha-IIb/beta-3
(Homo sapiens (Human)) | BDBM50083771
(2-(3,5-Dimethyl-isoxazole-4-sulfonylamino)-3-({5-[...)Show SMILES Cc1noc(C)c1S(=O)(=O)N[C@@H](CNC(=O)C1=NOC(CCCCNc2ncc[nH]2)C1)C(O)=O |t:17| Show InChI InChI=1S/C19H27N7O7S/c1-11-16(12(2)32-24-11)34(30,31)26-15(18(28)29)10-23-17(27)14-9-13(33-25-14)5-3-4-6-20-19-21-7-8-22-19/h7-8,13,15,26H,3-6,9-10H2,1-2H3,(H,23,27)(H,28,29)(H2,20,21,22)/t13?,15-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 1.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
DuPont Pharmaceuticals Company
Curated by ChEMBL
| Assay Description
Inhibition of platelet aggregation in human platelet rich plasma (PRP) |
J Med Chem 43: 27-40 (2000)
BindingDB Entry DOI: 10.7270/Q2571B77 |
More data for this
Ligand-Target Pair | |