Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 594.5 BDBM435340

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Diacylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM435340 ((trans)-N-((2-((5-cyclopropyl-1,2,4- oxadiazol-3-y...) Show SMILES Cc1noc(n1)[C@@H]1CC1C(=O)NCc1ccc(-c2cccc(OC(F)(F)F)c2)c2CCN(Cc3noc(n3)C3CC3)Cc12 |r| Show InChI InChI=1S/C30H29F3N6O4/c1-16-35-29(43-37-16)24-12-23(24)27(40)34-13-19-7-8-21(18-3-2-4-20(11-18)41-30(31,32)33)22-9-10-39(14-25(19)22)15-26-36-28(42-38-26)17-5-6-17/h2-4,7-8,11,17,23-24H,5-6,9-10,12-15H2,1H3,(H,34,40)/t23?,24-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description DGAT2 activity was determined by measuring the amount of enzymatic product triolein (1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membrane prep m...				US Patent US10568876 (2020) BindingDB Entry DOI: 10.7270/Q22B91FB
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