Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 228.2 BDBM50052554

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 1 (Homo sapiens (Human))	BDBM50052554 (2-Amino-6-(3-hydroxy-5-methyl-isoxazol-4-yl)-hexan...) Show SMILES Cc1o[nH]c(=O)c1CCCCC(N)C(O)=O Show InChI InChI=1S/C10H16N2O4/c1-6-7(9(13)12-16-6)4-2-3-5-8(11)10(14)15/h8H,2-5,11H2,1H3,(H,12,13)(H,14,15)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a
Royal Danish School of Pharmacy Curated by ChEMBL					Assay Description Agonistic activity at mGlu1-alpha receptor expressed in CHO cells				J Med Chem 39: 3188-94 (1996) Article DOI: 10.1021/jm9602569 BindingDB Entry DOI: 10.7270/Q2M909BH
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 6 (Homo sapiens (Human))	BDBM50052554 (2-Amino-6-(3-hydroxy-5-methyl-isoxazol-4-yl)-hexan...) Show SMILES Cc1o[nH]c(=O)c1CCCCC(N)C(O)=O Show InChI InChI=1S/C10H16N2O4/c1-6-7(9(13)12-16-6)4-2-3-5-8(11)10(14)15/h8H,2-5,11H2,1H3,(H,12,13)(H,14,15)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a
Royal Danish School of Pharmacy Curated by ChEMBL					Assay Description Agonistic activity at mGlu6 receptor expressed in CHO cells				J Med Chem 39: 3188-94 (1996) Article DOI: 10.1021/jm9602569 BindingDB Entry DOI: 10.7270/Q2M909BH
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50052554 (2-Amino-6-(3-hydroxy-5-methyl-isoxazol-4-yl)-hexan...) Show SMILES Cc1o[nH]c(=O)c1CCCCC(N)C(O)=O Show InChI InChI=1S/C10H16N2O4/c1-6-7(9(13)12-16-6)4-2-3-5-8(11)10(14)15/h8H,2-5,11H2,1H3,(H,12,13)(H,14,15)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a
Royal Danish School of Pharmacy Curated by ChEMBL					Assay Description Agonistic activity at mGlu2 receptor expressed in CHO cells				J Med Chem 39: 3188-94 (1996) Article DOI: 10.1021/jm9602569 BindingDB Entry DOI: 10.7270/Q2M909BH
					More data for this Ligand-Target Pair