Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM33292
(phenylpropanoic acid derivative, 17h | racemic)Show SMILES Cc1oc(nc1CCCc1ccc(CC(C(O)=O)n2ccnn2)cc1)-c1ccccc1 Show InChI InChI=1S/C24H24N4O3/c1-17-21(26-23(31-17)20-7-3-2-4-8-20)9-5-6-18-10-12-19(13-11-18)16-22(24(29)30)28-15-14-25-27-28/h2-4,7-8,10-15,22H,5-6,9,16H2,1H3,(H,29,30) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 1.40E+4 | n/a | >3.00E+4 | n/a | n/a | 7.4 | 23 |
Pfizer
| Assay Description
Human 6His-PPAR ligand-binding domain was added to the mixture containing radioligand and test compound, followed by yttrium silicate polylysine SPA ... |
Bioorg Med Chem 17: 7113-25 (2009)
Article DOI: 10.1016/j.bmc.2009.09.001
BindingDB Entry DOI: 10.7270/Q2BP0158 |
More data for this
Ligand-Target Pair | |
Peroxisome proliferator-activated receptor alpha
(Homo sapiens (Human)) | BDBM33292
(phenylpropanoic acid derivative, 17h | racemic)Show SMILES Cc1oc(nc1CCCc1ccc(CC(C(O)=O)n2ccnn2)cc1)-c1ccccc1 Show InChI InChI=1S/C24H24N4O3/c1-17-21(26-23(31-17)20-7-3-2-4-8-20)9-5-6-18-10-12-19(13-11-18)16-22(24(29)30)28-15-14-25-27-28/h2-4,7-8,10-15,22H,5-6,9,16H2,1H3,(H,29,30) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | >1.00E+5 | n/a | n/a | 7.2 | 15 |
Pfizer
| Assay Description
Human PPAR alpha receptor was expressed as recombinant glutathione-S-transferase (GST)-fusion proteins in Escherichia coli. The purified GST-hPPAR al... |
Bioorg Med Chem 17: 7113-25 (2009)
Article DOI: 10.1016/j.bmc.2009.09.001
BindingDB Entry DOI: 10.7270/Q2BP0158 |
More data for this
Ligand-Target Pair | |