Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 263.2 BDBM50536119

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Polymerase acidic protein (Hepatitis C virus)	BDBM50536119 (CHEMBL4536508) Show SMILES Cc1occ(O)c(=O)c1C(=O)Nc1ccc(F)cc1 Show InChI InChI=1S/C13H10FNO4/c1-7-11(12(17)10(16)6-19-7)13(18)15-9-4-2-8(14)3-5-9/h2-6,16H,1H3,(H,15,18)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of California San Diego Curated by ChEMBL					Assay Description Inhibition of 8-histidine tagged influenza virus H1N1 N-terminal PA endonuclease expressed in Escherichia coli BL21 cells using single-stranded 5'-FA...				J Med Chem 59: 6444-54 (2016) Article DOI: 10.1021/acs.jmedchem.6b00628 BindingDB Entry DOI: 10.7270/Q2W95DPM
					More data for this Ligand-Target Pair
Polymerase acidic protein (Hepatitis C virus)	BDBM50536119 (CHEMBL4536508) Show SMILES Cc1occ(O)c(=O)c1C(=O)Nc1ccc(F)cc1 Show InChI InChI=1S/C13H10FNO4/c1-7-11(12(17)10(16)6-19-7)13(18)15-9-4-2-8(14)3-5-9/h2-6,16H,1H3,(H,15,18)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>5.01E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of California San Diego Curated by ChEMBL					Assay Description Inhibition of 8-histidine tagged influenza virus H1N1 N-terminal PA endonuclease expressed in Escherichia coli BL21 cells using single-stranded 5'-FA...				J Med Chem 59: 6444-54 (2016) Article DOI: 10.1021/acs.jmedchem.6b00628 BindingDB Entry DOI: 10.7270/Q2W95DPM
					More data for this Ligand-Target Pair