Found 4 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Prolyl endopeptidase FAP
(Mus musculus (Mouse)) | BDBM50009372
(CHEMBL3233848)Show SMILES ClCC(=O)[C@@H]1CCCN1C(=O)CNC(=O)c1ccnc2ccccc12 |r| Show InChI InChI=1S/C18H18ClN3O3/c19-10-16(23)15-6-3-9-22(15)17(24)11-21-18(25)13-7-8-20-14-5-2-1-4-12(13)14/h1-2,4-5,7-8,15H,3,6,9-11H2,(H,21,25)/t15-/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
| Article PubMed
| n/a | n/a | 177 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Antwerp
Curated by ChEMBL
| Assay Description Inhibition of recombinant mouse FAP purified from HEK293 cell supernatant using Ala-Pro-p-nitroanilide as substrate by spectrophotometry |
J Med Chem 57: 3053-74 (2014)
Article DOI: 10.1021/jm500031w BindingDB Entry DOI: 10.7270/Q2P84DFW |
More data for this Ligand-Target Pair | |
Prolyl endopeptidase
(Homo sapiens (Human)) | BDBM50009372
(CHEMBL3233848)Show SMILES ClCC(=O)[C@@H]1CCCN1C(=O)CNC(=O)c1ccnc2ccccc12 |r| Show InChI InChI=1S/C18H18ClN3O3/c19-10-16(23)15-6-3-9-22(15)17(24)11-21-18(25)13-7-8-20-14-5-2-1-4-12(13)14/h1-2,4-5,7-8,15H,3,6,9-11H2,(H,21,25)/t15-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
| Article PubMed
| n/a | n/a | 780 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Antwerp
Curated by ChEMBL
| Assay Description Inhibition of recombinant human PREP purified from Escherichia coli using Z-Gly-Pro-p-nitroanilide as substrate by spectrophotometry |
J Med Chem 57: 3053-74 (2014)
Article DOI: 10.1021/jm500031w BindingDB Entry DOI: 10.7270/Q2P84DFW |
More data for this Ligand-Target Pair | |
Dipeptidyl peptidase 2
(Homo sapiens (Human)) | BDBM50009372
(CHEMBL3233848)Show SMILES ClCC(=O)[C@@H]1CCCN1C(=O)CNC(=O)c1ccnc2ccccc12 |r| Show InChI InChI=1S/C18H18ClN3O3/c19-10-16(23)15-6-3-9-22(15)17(24)11-21-18(25)13-7-8-20-14-5-2-1-4-12(13)14/h1-2,4-5,7-8,15H,3,6,9-11H2,(H,21,25)/t15-/m0/s1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
| Article PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Antwerp
Curated by ChEMBL
| Assay Description Inhibition of DPP2 purified from human seminal plasma using Lys-Ala-p-nitroanilide as substrate by spectrophotometry |
J Med Chem 57: 3053-74 (2014)
Article DOI: 10.1021/jm500031w BindingDB Entry DOI: 10.7270/Q2P84DFW |
More data for this Ligand-Target Pair | |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM50009372
(CHEMBL3233848)Show SMILES ClCC(=O)[C@@H]1CCCN1C(=O)CNC(=O)c1ccnc2ccccc12 |r| Show InChI InChI=1S/C18H18ClN3O3/c19-10-16(23)15-6-3-9-22(15)17(24)11-21-18(25)13-7-8-20-14-5-2-1-4-12(13)14/h1-2,4-5,7-8,15H,3,6,9-11H2,(H,21,25)/t15-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
| Article PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Antwerp
Curated by ChEMBL
| Assay Description Inhibition of DPP4 purified from human seminal plasma using Gly-Pro-p-nitroanilide as substrate by spectrophotometry |
J Med Chem 57: 3053-74 (2014)
Article DOI: 10.1021/jm500031w BindingDB Entry DOI: 10.7270/Q2P84DFW |
More data for this Ligand-Target Pair | |