Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 594.0 BDBM440642

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Programmed cell death 1 ligand 1 (Homo sapiens (Human))	BDBM440642 (US10639284, Compound 1.010 | US11426364, Compound ...) Show SMILES Clc1cc(CNCCn2nn[nH]c2=O)c(OCc2cncc(c2)C#N)cc1O[C@H]1CCc2c1cccc2-c1ccccc1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Plates were coated with 1 μg/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with PBS containing 2% ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2K93BSK
					More data for this Ligand-Target Pair
Programmed cell death 1 ligand 1 (Homo sapiens (Human))	BDBM440642 (US10639284, Compound 1.010 | US11426364, Compound ...) Show SMILES Clc1cc(CNCCn2nn[nH]c2=O)c(OCc2cncc(c2)C#N)cc1O[C@H]1CCc2c1cccc2-c1ccccc1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
ChemoCentryx, Inc. US Patent					Assay Description Plates were coated with 1 μg/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with PBS containing 2% BSA...				US Patent US10639284 (2020) BindingDB Entry DOI: 10.7270/Q25Q5043
					More data for this Ligand-Target Pair