Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 495.4 BDBM126713

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysosomal Pro-X carboxypeptidase (Homo sapiens (Human))	BDBM126713 (US8785634, 9) Show SMILES Clc1cc(Cl)cc(c1)C1OC2(CCN(Cc3ccc(nc3)N3CCCC3)CC2)c2ncccc12 Show InChI InChI=1S/C27H28Cl2N4O/c28-21-14-20(15-22(29)16-21)25-23-4-3-9-30-26(23)27(34-25)7-12-32(13-8-27)18-19-5-6-24(31-17-19)33-10-1-2-11-33/h3-6,9,14-17,25H,1-2,7-8,10-13,18H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	89	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp US Patent					Assay Description The potency of compounds of formula I against PrCP was determined by a fluorescence intensity kinetic assay measuring the IC50 values of PrCP inhibit...				US Patent US8785634 (2014) BindingDB Entry DOI: 10.7270/Q2HH6HRS
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