Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 488.0 BDBM50417475

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuropeptide Y receptor type 2 (Homo sapiens (Human))	BDBM50417475 (CHEMBL1288016) Show SMILES Clc1cc(NC(=O)C(c2ccccc2)c2ccccc2)ccc1N1CCC(CC1)N1CCCCC1 Show InChI InChI=1S/C30H34ClN3O/c31-27-22-25(14-15-28(27)34-20-16-26(17-21-34)33-18-8-3-9-19-33)32-30(35)29(23-10-4-1-5-11-23)24-12-6-2-7-13-24/h1-2,4-7,10-15,22,26,29H,3,8-9,16-21H2,(H,32,35)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	50.1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human NPY Y2 receptor in KAN-TS cells by [35]GTPgammaS assay				Bioorg Med Chem Lett 20: 7341-4 (2010) Article DOI: 10.1016/j.bmcl.2010.10.065 BindingDB Entry DOI: 10.7270/Q2BV7HWV
					More data for this Ligand-Target Pair
Neuropeptide Y-Y2 receptor (Rattus norvegicus)	BDBM50417475 (CHEMBL1288016) Show SMILES Clc1cc(NC(=O)C(c2ccccc2)c2ccccc2)ccc1N1CCC(CC1)N1CCCCC1 Show InChI InChI=1S/C30H34ClN3O/c31-27-22-25(14-15-28(27)34-20-16-26(17-21-34)33-18-8-3-9-19-33)32-30(35)29(23-10-4-1-5-11-23)24-12-6-2-7-13-24/h1-2,4-7,10-15,22,26,29H,3,8-9,16-21H2,(H,32,35)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	79.4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at rat NPY Y2 receptor expressed in HEK cells by [35]GTPgammaS assay				Bioorg Med Chem Lett 20: 7341-4 (2010) Article DOI: 10.1016/j.bmcl.2010.10.065 BindingDB Entry DOI: 10.7270/Q2BV7HWV
					More data for this Ligand-Target Pair