Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 431.3 BDBM50364389

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysosomal Pro-X carboxypeptidase (Homo sapiens (Human))	BDBM50364389 (CHEMBL1950313) Show SMILES Clc1cc2nc(CNC(=O)CCN3CCC(CC3)c3ccccc3)[nH]c2cc1Cl Show InChI InChI=1S/C22H24Cl2N4O/c23-17-12-19-20(13-18(17)24)27-21(26-19)14-25-22(29)8-11-28-9-6-16(7-10-28)15-4-2-1-3-5-15/h1-5,12-13,16H,6-11,14H2,(H,25,29)(H,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	427	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human recombinant PrCP using Mca-Ala-Pro-Lys(Dnp)-OH as substrate for 30 mins by continuous fluorimetric assay				Bioorg Med Chem Lett 22: 1774-8 (2012) Article DOI: 10.1016/j.bmcl.2011.12.064 BindingDB Entry DOI: 10.7270/Q27H1K28
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