Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 315.8 BDBM50317501

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM50317501 ((S)-2-((4-(4-chlorobenzyl)phenoxy)methyl)piperidin...) Show SMILES Clc1ccc(Cc2ccc(OC[C@@H]3CCCCN3)cc2)cc1 |r| Show InChI InChI=1S/C19H22ClNO/c20-17-8-4-15(5-9-17)13-16-6-10-19(11-7-16)22-14-18-3-1-2-12-21-18/h4-11,18,21H,1-3,12-14H2/t18-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	438	n/a	n/a	n/a	n/a	n/a	n/a
deCODE Chemistry, Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant LTA4H hydrolysis assessed as inhibition of LTB4 formation by LC-MS/MS				Bioorg Med Chem Lett 20: 2851-4 (2010) Article DOI: 10.1016/j.bmcl.2010.03.047 BindingDB Entry DOI: 10.7270/Q2CC10VD
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