Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 518.0 BDBM430769

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuromedin-K receptor (Homo sapiens (Human))	BDBM430769 ((3-(2-(4-chlorobenzyl)thiazol-4-yl)-5,6-dihydro-[1...) Show SMILES Clc1ccc(Cc2nc(cs2)-c2nnc3CN(CCn23)C(=O)c2ccc(cc2)-c2cccs2)cc1 Show InChI InChI=1S/C26H20ClN5OS2/c27-20-9-3-17(4-10-20)14-24-28-21(16-35-24)25-30-29-23-15-31(11-12-32(23)25)26(33)19-7-5-18(6-8-19)22-2-1-13-34-22/h1-10,13,16H,11-12,14-15H2	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Ogeda SA US Patent					Assay Description The ability of the compounds of the invention to inhibit the binding of the NK-3 receptor selective antagonist SB222200 was assessed by an in vitro r...				US Patent US10544150 (2020) BindingDB Entry DOI: 10.7270/Q2XW4N7G
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