Found 3 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Cystic fibrosis transmembrane conductance regulator
(Homo sapiens (Human)) | BDBM50164981
((S)-2-(3-Phenoxy-benzoyl)-1,2,3,4-tetrahydro-isoqu...)Show SMILES Clc1ccc(NC(=O)[C@@H]2Cc3ccccc3CN2C(=O)c2cccc(Oc3ccccc3)c2)cc1 Show InChI InChI=1S/C29H23ClN2O3/c30-23-13-15-24(16-14-23)31-28(33)27-18-20-7-4-5-8-22(20)19-32(27)29(34)21-9-6-12-26(17-21)35-25-10-2-1-3-11-25/h1-17,27H,18-19H2,(H,31,33)/t27-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 119 | n/a | n/a | n/a | n/a |
Genzyme Corp.
Curated by ChEMBL
| Assay Description Effective concentration for cellular chloride transport in C127 mouse epithelial cell transfected with recombinant Delta F508 CFTR |
Bioorg Med Chem Lett 15: 2087-91 (2005)
Article DOI: 10.1016/j.bmcl.2005.02.041 BindingDB Entry DOI: 10.7270/Q2J965WP |
More data for this Ligand-Target Pair | |
Cystic fibrosis transmembrane conductance regulator
(Homo sapiens (Human)) | BDBM50164989
((R)-2-(3-Phenoxy-benzoyl)-1,2,3,4-tetrahydro-isoqu...)Show SMILES Clc1ccc(NC(=O)[C@H]2Cc3ccccc3CN2C(=O)c2cccc(Oc3ccccc3)c2)cc1 Show InChI InChI=1S/C29H23ClN2O3/c30-23-13-15-24(16-14-23)31-28(33)27-18-20-7-4-5-8-22(20)19-32(27)29(34)21-9-6-12-26(17-21)35-25-10-2-1-3-11-25/h1-17,27H,18-19H2,(H,31,33)/t27-/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 336 | n/a | n/a | n/a | n/a |
Genzyme Corp.
Curated by ChEMBL
| Assay Description Effective concentration for cellular chloride transport in C127 mouse epithelial cell transfected with recombinant Delta F508 CFTR |
Bioorg Med Chem Lett 15: 2087-91 (2005)
Article DOI: 10.1016/j.bmcl.2005.02.041 BindingDB Entry DOI: 10.7270/Q2J965WP |
More data for this Ligand-Target Pair | |
Cystic fibrosis transmembrane conductance regulator
(Homo sapiens (Human)) | BDBM50164983
(2-(3-Phenoxy-benzoyl)-1,2,3,4-tetrahydro-isoquinol...)Show SMILES Clc1ccc(NC(=O)C2Cc3ccccc3CN2C(=O)c2cccc(Oc3ccccc3)c2)cc1 Show InChI InChI=1S/C29H23ClN2O3/c30-23-13-15-24(16-14-23)31-28(33)27-18-20-7-4-5-8-22(20)19-32(27)29(34)21-9-6-12-26(17-21)35-25-10-2-1-3-11-25/h1-17,27H,18-19H2,(H,31,33) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 294 | n/a | n/a | n/a | n/a |
Genzyme Corp.
Curated by ChEMBL
| Assay Description Effective concentration for cellular chloride transport in C127 mouse epithelial cell transfected with recombinant Delta F508 CFTR |
Bioorg Med Chem Lett 15: 2087-91 (2005)
Article DOI: 10.1016/j.bmcl.2005.02.041 BindingDB Entry DOI: 10.7270/Q2J965WP |
More data for this Ligand-Target Pair | |