Found 4 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Neuropeptide Y receptor type 1
(Homo sapiens (Human)) | BDBM50060730
(1'-[2-(4-Chloro-phenoxymethyl)-1-(2-piperidin-1-yl...)Show SMILES Clc1ccc(OCc2c(CN3CCC(CC3)N3CCCCC3)c3ccccc3n2CCN2CCCCC2)cc1 Show InChI InChI=1S/C33H45ClN4O/c34-27-11-13-29(14-12-27)39-26-33-31(25-36-21-15-28(16-22-36)37-19-7-2-8-20-37)30-9-3-4-10-32(30)38(33)24-23-35-17-5-1-6-18-35/h3-4,9-14,28H,1-2,5-8,15-26H2 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 98 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description Binding affinity for Neuropeptide Y receptor type 1 expressed in AV-12 cells |
J Med Chem 40: 3712-4 (1997)
Article DOI: 10.1021/jm970512x BindingDB Entry DOI: 10.7270/Q2HQ3Z1P |
More data for this Ligand-Target Pair | |
Neuropeptide Y receptor type 4
(Homo sapiens (Human)) | BDBM50060730
(1'-[2-(4-Chloro-phenoxymethyl)-1-(2-piperidin-1-yl...)Show SMILES Clc1ccc(OCc2c(CN3CCC(CC3)N3CCCCC3)c3ccccc3n2CCN2CCCCC2)cc1 Show InChI InChI=1S/C33H45ClN4O/c34-27-11-13-29(14-12-27)39-26-33-31(25-36-21-15-28(16-22-36)37-19-7-2-8-20-37)30-9-3-4-10-32(30)38(33)24-23-35-17-5-1-6-18-35/h3-4,9-14,28H,1-2,5-8,15-26H2 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description Affinity for human Neuropeptide Y receptor type 4 |
J Med Chem 40: 3712-4 (1997)
Article DOI: 10.1021/jm970512x BindingDB Entry DOI: 10.7270/Q2HQ3Z1P |
More data for this Ligand-Target Pair | |
Neuropeptide Y receptor type 5
(Homo sapiens (Human)) | BDBM50060730
(1'-[2-(4-Chloro-phenoxymethyl)-1-(2-piperidin-1-yl...)Show SMILES Clc1ccc(OCc2c(CN3CCC(CC3)N3CCCCC3)c3ccccc3n2CCN2CCCCC2)cc1 Show InChI InChI=1S/C33H45ClN4O/c34-27-11-13-29(14-12-27)39-26-33-31(25-36-21-15-28(16-22-36)37-19-7-2-8-20-37)30-9-3-4-10-32(30)38(33)24-23-35-17-5-1-6-18-35/h3-4,9-14,28H,1-2,5-8,15-26H2 | KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description Affinity for human Neuropeptide Y receptor type 5 |
J Med Chem 40: 3712-4 (1997)
Article DOI: 10.1021/jm970512x BindingDB Entry DOI: 10.7270/Q2HQ3Z1P |
More data for this Ligand-Target Pair | |
Neuropeptide Y receptor type 2
(Homo sapiens (Human)) | BDBM50060730
(1'-[2-(4-Chloro-phenoxymethyl)-1-(2-piperidin-1-yl...)Show SMILES Clc1ccc(OCc2c(CN3CCC(CC3)N3CCCCC3)c3ccccc3n2CCN2CCCCC2)cc1 Show InChI InChI=1S/C33H45ClN4O/c34-27-11-13-29(14-12-27)39-26-33-31(25-36-21-15-28(16-22-36)37-19-7-2-8-20-37)30-9-3-4-10-32(30)38(33)24-23-35-17-5-1-6-18-35/h3-4,9-14,28H,1-2,5-8,15-26H2 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description Affinity for human Neuropeptide Y receptor type 2 |
J Med Chem 40: 3712-4 (1997)
Article DOI: 10.1021/jm970512x BindingDB Entry DOI: 10.7270/Q2HQ3Z1P |
More data for this Ligand-Target Pair | |