Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Cyclin-dependent kinase 1
(Homo sapiens (Human)) | BDBM50295601
(3-({3-[(4-chlorophenoxy)methyl][1,2,4]triazolo[3,4...)Show SMILES Clc1ccc(OCc2nnc3sc(Cc4[nH]nc5[nH]c(=S)[nH]c(=S)c45)nn23)cc1 Show InChI InChI=1S/C16H11ClN8OS3/c17-7-1-3-8(4-2-7)26-6-10-21-23-16-25(10)24-11(29-16)5-9-12-13(22-20-9)18-15(28)19-14(12)27/h1-4H,5-6H2,(H3,18,19,20,22,27,28) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.90E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
National Organization for Drug Control and Research
Curated by ChEMBL
| Assay Description
Inhibition of CDK1/Cyclin B |
Eur J Med Chem 44: 2776-81 (2009)
Article DOI: 10.1016/j.ejmech.2009.01.003
BindingDB Entry DOI: 10.7270/Q2833S2P |
More data for this
Ligand-Target Pair | |
Cyclin-dependent kinase 2
(Homo sapiens (Human)) | BDBM50295601
(3-({3-[(4-chlorophenoxy)methyl][1,2,4]triazolo[3,4...)Show SMILES Clc1ccc(OCc2nnc3sc(Cc4[nH]nc5[nH]c(=S)[nH]c(=S)c45)nn23)cc1 Show InChI InChI=1S/C16H11ClN8OS3/c17-7-1-3-8(4-2-7)26-6-10-21-23-16-25(10)24-11(29-16)5-9-12-13(22-20-9)18-15(28)19-14(12)27/h1-4H,5-6H2,(H3,18,19,20,22,27,28) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
National Organization for Drug Control and Research
Curated by ChEMBL
| Assay Description
Inhibition of CDK2/Cyclin A |
Eur J Med Chem 44: 2776-81 (2009)
Article DOI: 10.1016/j.ejmech.2009.01.003
BindingDB Entry DOI: 10.7270/Q2833S2P |
More data for this
Ligand-Target Pair | |