Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 382.8 BDBM206766

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 1 (Homo sapiens (Human))	BDBM206766 (US9260448, 68) Show SMILES Clc1ccc(cc1)-n1cnc2c(csc2c1=O)-c1ccc2OCOc2c1 Show InChI InChI=1S/C19H11ClN2O3S/c20-12-2-4-13(5-3-12)22-9-21-17-14(8-26-18(17)19(22)23)11-1-6-15-16(7-11)25-10-24-15/h1-9H,10H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	447	n/a	n/a	n/a	n/a	n/a	n/a
KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY US Patent					Assay Description Cells of Chem3 Cell Line (HTS145C:Millipore) in which mGluR1 was stably expressed were adjusted to a density of 2×106/ml. 50 μl of the cells wer...				US Patent US9260448 (2016) BindingDB Entry DOI: 10.7270/Q2H9941W
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