Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 435.3 BDBM50507035

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Polymerase acidic protein (Hepatitis C virus)	BDBM50507035 (CHEMBL4542541) Show SMILES Clc1ccc(cc1)N1CCN=C1c1ccc(cc1)C1=NCCN1c1ccc(Cl)cc1 |c:11,t:21| Show InChI InChI=1S/C24H20Cl2N4/c25-19-5-9-21(10-6-19)29-15-13-27-23(29)17-1-2-18(4-3-17)24-28-14-16-30(24)22-11-7-20(26)8-12-22/h1-12H,13-16H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Saint Petersburg State University Curated by ChEMBL					Assay Description Inhibition of Influenza A virus (A/Puerto Rico/8/34(H1N1)) PA endonuclease infected in MDCK cells assessed as reduction in virus titer treated with c...				Eur J Med Chem 161: 526-532 (2019) Article DOI: 10.1016/j.ejmech.2018.10.063 BindingDB Entry DOI: 10.7270/Q2ZW1Q61
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