Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 196.6 BDBM50001897Purchase

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 5 hits in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 3A (RAT)	BDBM50001897 (1-(4-Chloro-phenyl)-piperazine | CHEMBL114478 | pC...) Show SMILES Clc1ccc(cc1)N1CCNCC1 Show InChI InChI=1S/C10H13ClN2/c11-9-1-3-10(4-2-9)13-7-5-12-6-8-13/h1-4,12H,5-8H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	120	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by PDSP Ki Database									Eur J Pharmacol 168: 387-92 (1989) Article DOI: 10.1016/0014-2999(89)90802-9 BindingDB Entry DOI: 10.7270/Q23R0RC5
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50001897 (1-(4-Chloro-phenyl)-piperazine | CHEMBL114478 | pC...) Show SMILES Clc1ccc(cc1)N1CCNCC1 Show InChI InChI=1S/C10H13ClN2/c11-9-1-3-10(4-2-9)13-7-5-12-6-8-13/h1-4,12H,5-8H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	1.15E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Binding affinity of the compound towards sigma receptor in guinea pig brain membranes using [3H]-DTG as radioligand				J Med Chem 34: 3360-5 (1992) BindingDB Entry DOI: 10.7270/Q2MC8XZR
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 3A/3B/3C/3D/3E (Homo sapiens (Human))	BDBM50001897 (1-(4-Chloro-phenyl)-piperazine | CHEMBL114478 | pC...) Show SMILES Clc1ccc(cc1)N1CCNCC1 Show InChI InChI=1S/C10H13ClN2/c11-9-1-3-10(4-2-9)13-7-5-12-6-8-13/h1-4,12H,5-8H2	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	2.16E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Compound was tested for the inhibition of [3H]-GR-65,630 binding to 5-hydroxytryptamine 3 receptor expressed in NG 108-15 cells				J Med Chem 39: 4017-26 (1996) Article DOI: 10.1021/jm9603936 BindingDB Entry DOI: 10.7270/Q23F4NQT
					More data for this Ligand-Target Pair
Beta-1 adrenergic receptor (Homo sapiens (Human))	BDBM50001897 (1-(4-Chloro-phenyl)-piperazine | CHEMBL114478 | pC...) Show SMILES Clc1ccc(cc1)N1CCNCC1 Show InChI InChI=1S/C10H13ClN2/c11-9-1-3-10(4-2-9)13-7-5-12-6-8-13/h1-4,12H,5-8H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Berlex Laboratories Curated by ChEMBL					Assay Description Binding affinity for Beta-1 adrenergic receptor by displacing [3H]dihydroalprenolol, in partially purified membrane fractions from canine ventricular...				J Med Chem 35: 743-50 (1992) BindingDB Entry DOI: 10.7270/Q2319TT0
					More data for this Ligand-Target Pair
Beta-2 adrenergic receptor (Canis familiaris)	BDBM50001897 (1-(4-Chloro-phenyl)-piperazine | CHEMBL114478 | pC...) Show SMILES Clc1ccc(cc1)N1CCNCC1 Show InChI InChI=1S/C10H13ClN2/c11-9-1-3-10(4-2-9)13-7-5-12-6-8-13/h1-4,12H,5-8H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	7.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Berlex Laboratories Curated by ChEMBL					Assay Description Binding affinity towards Beta-2 adrenergic receptor by displacing [3H]dihydroalprenolol, in partially purified membrane fractions from canine lung ti...				J Med Chem 35: 743-50 (1992) BindingDB Entry DOI: 10.7270/Q2319TT0
					More data for this Ligand-Target Pair