Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 504.9 BDBM50320161

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-X-C chemokine receptor type 3 (Homo sapiens (Human))	BDBM50320161 (CHEMBL1083309 | N-(4-(1H-tetrazol-5-yl)benzyl)-4-c...) Show SMILES Clc1ccc(cc1)S(=O)(=O)N(CCc1cc2ccccc2cn1)Cc1ccc(cc1)-c1nnn[nH]1 Show InChI InChI=1S/C25H21ClN6O2S/c26-22-9-11-24(12-10-22)35(33,34)32(14-13-23-15-20-3-1-2-4-21(20)16-27-23)17-18-5-7-19(8-6-18)25-28-30-31-29-25/h1-12,15-16H,13-14,17H2,(H,28,29,30,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	911	n/a	n/a	n/a	n/a	n/a	n/a
Merck Serono SA Curated by ChEMBL					Assay Description Antagonist activity at human CXCR3 expressed in mouse L1.2 cells assessed as inhibition of IP10-induced chemotaxis after 4 hrs				Bioorg Med Chem Lett 20: 3614-7 (2010) Article DOI: 10.1016/j.bmcl.2010.04.113 BindingDB Entry DOI: 10.7270/Q2668DDX
					More data for this Ligand-Target Pair