Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 511.0 BDBM50320131

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-X-C chemokine receptor type 3 (Homo sapiens (Human))	BDBM50320131 (4-((N-benzyl-4-chlorophenylsulfonamido)methyl)-N-(...) Show SMILES Clc1ccc(cc1)S(=O)(=O)N(Cc1ccccc1)Cc1ccc(cc1)C(=O)NCc1cccs1 Show InChI InChI=1S/C26H23ClN2O3S2/c27-23-12-14-25(15-13-23)34(31,32)29(18-20-5-2-1-3-6-20)19-21-8-10-22(11-9-21)26(30)28-17-24-7-4-16-33-24/h1-16H,17-19H2,(H,28,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	192	n/a	n/a	n/a	n/a	n/a	n/a
Merck Serono SA Curated by ChEMBL					Assay Description Antagonist activity at human CXCR3 expressed in mouse L1.2 cells assessed as inhibition of IP10-induced chemotaxis after 4 hrs				Bioorg Med Chem Lett 20: 3614-7 (2010) Article DOI: 10.1016/j.bmcl.2010.04.113 BindingDB Entry DOI: 10.7270/Q2668DDX
					More data for this Ligand-Target Pair