Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 378.8 BDBM207924

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Alpha-synuclein (Homo sapiens (Human))	BDBM207924 (US9266832, Cpd081) Show SMILES Clc1ccc2[nH]cc(CCNC(=O)c3ccc(Cc4ccoc4)cc3)c2c1 Show InChI InChI=1S/C22H19ClN2O2/c23-19-5-6-21-20(12-19)18(13-25-21)7-9-24-22(26)17-3-1-15(2-4-17)11-16-8-10-27-14-16/h1-6,8,10,12-14,25H,7,9,11H2,(H,24,26)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	23	n/a	n/a	n/a	n/a
Katholieke Universiteit Levun; K. U. Leuven R&D reMYND US Patent					Assay Description α-Synucleinopathies are characterised by aggregation of α-synuclein in neurons. Aggregation of purified α-synuclein is performed essen...				US Patent US9266832 (2016) BindingDB Entry DOI: 10.7270/Q2319TP6
					More data for this Ligand-Target Pair