Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 414.8 BDBM207907

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Alpha-synuclein (Homo sapiens (Human))	BDBM207907 (US9266832, Cpd064) Show SMILES Clc1ccc2[nH]cc(CCNC(=O)c3cccc(Nc4cccc(c4)C#N)c3)c2c1 Show InChI InChI=1S/C24H19ClN4O/c25-19-7-8-23-22(13-19)18(15-28-23)9-10-27-24(30)17-4-2-6-21(12-17)29-20-5-1-3-16(11-20)14-26/h1-8,11-13,15,28-29H,9-10H2,(H,27,30)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	122	n/a	n/a	n/a	n/a
Katholieke Universiteit Levun; K. U. Leuven R&D reMYND US Patent					Assay Description α-Synucleinopathies are characterised by aggregation of α-synuclein in neurons. Aggregation of purified α-synuclein is performed essen...				US Patent US9266832 (2016) BindingDB Entry DOI: 10.7270/Q2319TP6
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