Found 2 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Lysosomal Pro-X carboxypeptidase
(Homo sapiens (Human)) | BDBM193283
(US9193762, RS-37-02)Show SMILES Clc1cccc(CNC(=O)CCCNC(=O)[C@@H]2CCCN2C(=O)OCc2ccccc2)c1 |r| Show InChI InChI=1S/C24H28ClN3O4/c25-20-10-4-9-19(15-20)16-27-22(29)12-5-13-26-23(30)21-11-6-14-28(21)24(31)32-17-18-7-2-1-3-8-18/h1-4,7-10,15,21H,5-6,11-14,16-17H2,(H,26,30)(H,27,29)/t21-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| US Patent
| 2.28E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
UNIVERSITY OF MISSISSIPPI
US Patent
| Assay Description Briefly, rPRCP was incubated in the presence or absence of various PRCP inhibitors in HEPES-carbonated buffer containing 1 mM Ala-Pro-paranitroanilin... |
US Patent US9193762 (2015)
BindingDB Entry DOI: 10.7270/Q2ST7NN2 |
More data for this Ligand-Target Pair | |
Lysosomal Pro-X carboxypeptidase
(Homo sapiens (Human)) | BDBM193283
(US9193762, RS-37-02)Show SMILES Clc1cccc(CNC(=O)CCCNC(=O)[C@@H]2CCCN2C(=O)OCc2ccccc2)c1 |r| Show InChI InChI=1S/C24H28ClN3O4/c25-20-10-4-9-19(15-20)16-27-22(29)12-5-13-26-23(30)21-11-6-14-28(21)24(31)32-17-18-7-2-1-3-8-18/h1-4,7-10,15,21H,5-6,11-14,16-17H2,(H,26,30)(H,27,29)/t21-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| US Patent
| 5.66E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
UNIVERSITY OF MISSISSIPPI
US Patent
| Assay Description Human pulmonary artery endothelial cells (HPAEC) were purchased from Invitrogen (Carlsbad, Calif.) and were cultured as previously described.20 The c... |
US Patent US9193762 (2015)
BindingDB Entry DOI: 10.7270/Q2ST7NN2 |
More data for this Ligand-Target Pair | |