Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 550.4 BDBM176329

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human))	BDBM176329 (US9688696, 44) Show SMILES Clc1cccc(Cl)c1NC(=O)N1CCC(CC1)c1ccc(cc1)-n1cnn(CCCc2ccccc2)c1=O Show InChI InChI=1S/C29H29Cl2N5O2/c30-25-9-4-10-26(31)27(25)33-28(37)34-18-15-23(16-19-34)22-11-13-24(14-12-22)35-20-32-36(29(35)38)17-5-8-21-6-2-1-3-7-21/h1-4,6-7,9-14,20,23H,5,8,15-19H2,(H,33,37)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	933	n/a	n/a	n/a	n/a	7.4	25
Janssen Pharmaceutica N.V. US Patent					Assay Description DGAT activity in membrane preparations was assayed in 50 mM Tris-HCl (pH 7.4), 150 mM MgCl2, 1 mM EDTA and 0.2% BSA, containing 50 μM DAG, 32 &#...				US Patent US9688696 (2017) BindingDB Entry DOI: 10.7270/Q24X55ZP
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