Found 6 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM50449596
(CHEMBL4163080)Show SMILES Clc1ccccc1OCCCCCCOc1cccc(\C=C2/N=C3SCCCN3C2=O)c1 |t:23| Show InChI InChI=1S/C25H27ClN2O3S/c26-21-11-3-4-12-23(21)31-15-6-2-1-5-14-30-20-10-7-9-19(17-20)18-22-24(29)28-13-8-16-32-25(28)27-22/h3-4,7,9-12,17-18H,1-2,5-6,8,13-16H2/b22-18- | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| Article
PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bonn
Curated by ChEMBL
| Assay Description
Displacement of [3H]CP55940 from recombinant human CB1 receptor expressed in CHO cell membranes after 2 hrs by liquid scintillation counting method |
Eur J Med Chem 155: 381-397 (2018)
Article DOI: 10.1016/j.ejmech.2018.05.050
BindingDB Entry DOI: 10.7270/Q22F7R1X |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50449596
(CHEMBL4163080)Show SMILES Clc1ccccc1OCCCCCCOc1cccc(\C=C2/N=C3SCCCN3C2=O)c1 |t:23| Show InChI InChI=1S/C25H27ClN2O3S/c26-21-11-3-4-12-23(21)31-15-6-2-1-5-14-30-20-10-7-9-19(17-20)18-22-24(29)28-13-8-16-32-25(28)27-22/h3-4,7,9-12,17-18H,1-2,5-6,8,13-16H2/b22-18- | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bonn
Curated by ChEMBL
| Assay Description
Displacement of [3H]CP55940 from recombinant human CB2 receptor expressed in CHO cell membranes after 2 hrs by liquid scintillation counting method |
Eur J Med Chem 155: 381-397 (2018)
Article DOI: 10.1016/j.ejmech.2018.05.050
BindingDB Entry DOI: 10.7270/Q22F7R1X |
More data for this
Ligand-Target Pair | |
G-protein coupled receptor 55
(Homo sapiens (Human)) | BDBM50449596
(CHEMBL4163080)Show SMILES Clc1ccccc1OCCCCCCOc1cccc(\C=C2/N=C3SCCCN3C2=O)c1 |t:23| Show InChI InChI=1S/C25H27ClN2O3S/c26-21-11-3-4-12-23(21)31-15-6-2-1-5-14-30-20-10-7-9-19(17-20)18-22-24(29)28-13-8-16-32-25(28)27-22/h3-4,7,9-12,17-18H,1-2,5-6,8,13-16H2/b22-18- | Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 3.41E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bonn
Curated by ChEMBL
| Assay Description
Antagonist activity at recombinant human GPR55 expressed in CHO cells assessed as inhibition of lysophosphatidylinositol-induced beta-arrestin recrui... |
Eur J Med Chem 155: 381-397 (2018)
Article DOI: 10.1016/j.ejmech.2018.05.050
BindingDB Entry DOI: 10.7270/Q22F7R1X |
More data for this
Ligand-Target Pair | |
N-arachidonyl glycine receptor
(Homo sapiens (Human)) | BDBM50449596
(CHEMBL4163080)Show SMILES Clc1ccccc1OCCCCCCOc1cccc(\C=C2/N=C3SCCCN3C2=O)c1 |t:23| Show InChI InChI=1S/C25H27ClN2O3S/c26-21-11-3-4-12-23(21)31-15-6-2-1-5-14-30-20-10-7-9-19(17-20)18-22-24(29)28-13-8-16-32-25(28)27-22/h3-4,7,9-12,17-18H,1-2,5-6,8,13-16H2/b22-18- | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bonn
Curated by ChEMBL
| Assay Description
Antagonist activity at recombinant human GPR18 expressed in CHO cells assessed as inhibition of delta9-THC-induced beta-arrestin recruitment preincub... |
Eur J Med Chem 155: 381-397 (2018)
Article DOI: 10.1016/j.ejmech.2018.05.050
BindingDB Entry DOI: 10.7270/Q22F7R1X |
More data for this
Ligand-Target Pair | |
G-protein coupled receptor 55
(Homo sapiens (Human)) | BDBM50449596
(CHEMBL4163080)Show SMILES Clc1ccccc1OCCCCCCOc1cccc(\C=C2/N=C3SCCCN3C2=O)c1 |t:23| Show InChI InChI=1S/C25H27ClN2O3S/c26-21-11-3-4-12-23(21)31-15-6-2-1-5-14-30-20-10-7-9-19(17-20)18-22-24(29)28-13-8-16-32-25(28)27-22/h3-4,7,9-12,17-18H,1-2,5-6,8,13-16H2/b22-18- | Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
University of Bonn
Curated by ChEMBL
| Assay Description
Agonist activity at recombinant human GPR55 expressed in CHO cells assessed as increase in beta-arrestin recruitment incubated for 60 mins measured f... |
Eur J Med Chem 155: 381-397 (2018)
Article DOI: 10.1016/j.ejmech.2018.05.050
BindingDB Entry DOI: 10.7270/Q22F7R1X |
More data for this
Ligand-Target Pair | |
N-arachidonyl glycine receptor
(Homo sapiens (Human)) | BDBM50449596
(CHEMBL4163080)Show SMILES Clc1ccccc1OCCCCCCOc1cccc(\C=C2/N=C3SCCCN3C2=O)c1 |t:23| Show InChI InChI=1S/C25H27ClN2O3S/c26-21-11-3-4-12-23(21)31-15-6-2-1-5-14-30-20-10-7-9-19(17-20)18-22-24(29)28-13-8-16-32-25(28)27-22/h3-4,7,9-12,17-18H,1-2,5-6,8,13-16H2/b22-18- | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
University of Bonn
Curated by ChEMBL
| Assay Description
Agonist activity at recombinant human GPR18 expressed in CHO cells assessed as increase in beta-arrestin recruitment incubated for 60 mins measured f... |
Eur J Med Chem 155: 381-397 (2018)
Article DOI: 10.1016/j.ejmech.2018.05.050
BindingDB Entry DOI: 10.7270/Q22F7R1X |
More data for this
Ligand-Target Pair | |