Found 2 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Acyl-CoA desaturase 1
(Rattus norvegicus (Rat)) | BDBM50429983
(CHEMBL2334633)Show SMILES Clc1ccccc1Oc1ccc(cc1)-c1nc2ccc(cc2[nH]1)C(=O)NCCC1CC1 Show InChI InChI=1S/C25H22ClN3O2/c26-20-3-1-2-4-23(20)31-19-10-7-17(8-11-19)24-28-21-12-9-18(15-22(21)29-24)25(30)27-14-13-16-5-6-16/h1-4,7-12,15-16H,5-6,13-14H2,(H,27,30)(H,28,29) | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 966 | n/a | n/a | n/a | n/a | n/a | n/a |
Sanofi-Aventis Deutschland GmbH
Curated by ChEMBL
| Assay Description Inhibition of SCD1 in Wistar rat liver microsomes using [14C] stearic acid as substrate incubated for 10 mins prior to substrate addition measured af... |
Bioorg Med Chem Lett 23: 1817-22 (2013)
Article DOI: 10.1016/j.bmcl.2013.01.030 BindingDB Entry DOI: 10.7270/Q2251KJJ |
More data for this Ligand-Target Pair | |
Stearoyl-CoA desaturase
(Homo sapiens (Human)) | BDBM50429983
(CHEMBL2334633)Show SMILES Clc1ccccc1Oc1ccc(cc1)-c1nc2ccc(cc2[nH]1)C(=O)NCCC1CC1 Show InChI InChI=1S/C25H22ClN3O2/c26-20-3-1-2-4-23(20)31-19-10-7-17(8-11-19)24-28-21-12-9-18(15-22(21)29-24)25(30)27-14-13-16-5-6-16/h1-4,7-12,15-16H,5-6,13-14H2,(H,27,30)(H,28,29) | PDB
KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 2.34E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Sanofi-Aventis Deutschland GmbH
Curated by ChEMBL
| Assay Description Inhibition of SCD1 in human HepG2 cells |
Bioorg Med Chem Lett 23: 1817-22 (2013)
Article DOI: 10.1016/j.bmcl.2013.01.030 BindingDB Entry DOI: 10.7270/Q2251KJJ |
More data for this Ligand-Target Pair | |