Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 435.9 BDBM50268350

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Muscarinic acetylcholine receptor M4 (Homo sapiens (Human))	BDBM50268350 (CHEMBL4098893) Show SMILES Clc1ccccc1S(=O)(=O)N1CCN(CC1)c1ccc(nn1)N1CCCCC1=O Show InChI InChI=1S/C19H22ClN5O3S/c20-15-5-1-2-6-16(15)29(27,28)24-13-11-23(12-14-24)17-8-9-18(22-21-17)25-10-4-3-7-19(25)26/h1-2,5-6,8-9H,3-4,7,10-14H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Technology Curated by ChEMBL					Assay Description Antagonist activity at human recombinant muscarinic M4 receptor expressed in CHO cells co-transfected with Gqi5 in presence of EC80 acetylcholine by ...				J Med Chem 34: 1879-84 (1991) Article DOI: 10.1016/j.bmcl.2017.05.042 BindingDB Entry DOI: 10.7270/Q29G5KR1
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