Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 436.8 BDBM307970

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclin-dependent kinase 9 (Homo sapiens (Human))	BDBM307970 (N-{5-chloro-4-[1-(tetrahydro-2H-pyran-4-ylmethyl)-...) Show SMILES Clc1cnc(NC(=O)c2cn[nH]c2)cc1-c1ccc2ncn(CC3CCOCC3)c2c1 Show InChI InChI=1S/C22H21ClN6O2/c23-18-11-24-21(28-22(30)16-9-26-27-10-16)8-17(18)15-1-2-19-20(7-15)29(13-25-19)12-14-3-5-31-6-4-14/h1-2,7-11,13-14H,3-6,12H2,(H,26,27)(H,24,28,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	190	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc. US Patent					Assay Description CDK9 enzyme activities were measured using LANCE ULight TR-FRET kinase assay reagents (PerkinElmer, Waltham, Mass.). Compounds were directly added in...				US Patent US9650358 (2017) BindingDB Entry DOI: 10.7270/Q2057J0M
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