Found 3 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Mitogen-activated protein kinase 10
(Homo sapiens (Human)) | BDBM351728
(N-(4-chloro-3-(1H-1,2,4-triazol-3-yl)thiophen-2-yl...)Show SMILES Clc1csc(NC(=O)Cn2c3ccc(cc3ccc2=O)C#N)c1-c1nc[nH]n1 Show InChI InChI=1S/C18H11ClN6O2S/c19-12-8-28-18(16(12)17-21-9-22-24-17)23-14(26)7-25-13-3-1-10(6-20)5-11(13)2-4-15(25)27/h1-5,8-9H,7H2,(H,23,26)(H,21,22,24) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
IMAGO PHARMACEUTICALS, INC.
US Patent
| Assay Description (1) Assay buffer #1 with 0.0025% Tween and 1 mM DTT was prepared using JNK buffer stock solution.(2) Assay buffer #2 with 0.025% BSA was prepared usi... |
US Patent US9796706 (2017)
BindingDB Entry DOI: 10.7270/Q24T6MHK |
More data for this Ligand-Target Pair | |
Mitogen-activated protein kinase 9
(Homo sapiens (Human)) | BDBM351728
(N-(4-chloro-3-(1H-1,2,4-triazol-3-yl)thiophen-2-yl...)Show SMILES Clc1csc(NC(=O)Cn2c3ccc(cc3ccc2=O)C#N)c1-c1nc[nH]n1 Show InChI InChI=1S/C18H11ClN6O2S/c19-12-8-28-18(16(12)17-21-9-22-24-17)23-14(26)7-25-13-3-1-10(6-20)5-11(13)2-4-15(25)27/h1-5,8-9H,7H2,(H,23,26)(H,21,22,24) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
IMAGO PHARMACEUTICALS, INC.
US Patent
| Assay Description (1) Assay buffer #1 with 0.0025% Tween and 1 mM DTT was prepared using JNK buffer stock solution.(2) Assay buffer #2 with 0.025% BSA was prepared usi... |
US Patent US9796706 (2017)
BindingDB Entry DOI: 10.7270/Q24T6MHK |
More data for this Ligand-Target Pair | |
Mitogen-activated protein kinase 8
(Homo sapiens (Human)) | BDBM351728
(N-(4-chloro-3-(1H-1,2,4-triazol-3-yl)thiophen-2-yl...)Show SMILES Clc1csc(NC(=O)Cn2c3ccc(cc3ccc2=O)C#N)c1-c1nc[nH]n1 Show InChI InChI=1S/C18H11ClN6O2S/c19-12-8-28-18(16(12)17-21-9-22-24-17)23-14(26)7-25-13-3-1-10(6-20)5-11(13)2-4-15(25)27/h1-5,8-9H,7H2,(H,23,26)(H,21,22,24) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
IMAGO PHARMACEUTICALS, INC.
US Patent
| Assay Description (1) Assay buffer #1 with 0.0025% Tween and 1 mM DTT was prepared using JNK buffer stock solution.(2) Assay buffer #2 with 0.025% BSA was prepared usi... |
US Patent US9796706 (2017)
BindingDB Entry DOI: 10.7270/Q24T6MHK |
More data for this Ligand-Target Pair | |