Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 368.9 BDBM50060727

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 5 hits in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuropeptide Y receptor type 1 (Homo sapiens (Human))	BDBM50060727 (2-(4-Chloro-phenoxymethyl)-1-methyl-3-piperidin-1-...) Show SMILES Cn1c(COc2ccc(Cl)cc2)c(CN2CCCCC2)c2ccccc12 Show InChI InChI=1S/C22H25ClN2O/c1-24-21-8-4-3-7-19(21)20(15-25-13-5-2-6-14-25)22(24)16-26-18-11-9-17(23)10-12-18/h3-4,7-12H,2,5-6,13-16H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	2.31E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description In vitro binding affinity towards human neuropeptide Y receptor type 1, determined by measuring its ability to displace [125]peptide YY				J Med Chem 41: 2709-19 (1998) Article DOI: 10.1021/jm9706630 BindingDB Entry DOI: 10.7270/Q2TD9WGN
					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 1 (Homo sapiens (Human))	BDBM50060727 (2-(4-Chloro-phenoxymethyl)-1-methyl-3-piperidin-1-...) Show SMILES Cn1c(COc2ccc(Cl)cc2)c(CN2CCCCC2)c2ccccc12 Show InChI InChI=1S/C22H25ClN2O/c1-24-21-8-4-3-7-19(21)20(15-25-13-5-2-6-14-25)22(24)16-26-18-11-9-17(23)10-12-18/h3-4,7-12H,2,5-6,13-16H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	2.32E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Binding affinity for Neuropeptide Y receptor type 1 expressed in AV-12 cells				J Med Chem 40: 3712-4 (1997) Article DOI: 10.1021/jm970512x BindingDB Entry DOI: 10.7270/Q2HQ3Z1P
					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 4 (Homo sapiens (Human))	BDBM50060727 (2-(4-Chloro-phenoxymethyl)-1-methyl-3-piperidin-1-...) Show SMILES Cn1c(COc2ccc(Cl)cc2)c(CN2CCCCC2)c2ccccc12 Show InChI InChI=1S/C22H25ClN2O/c1-24-21-8-4-3-7-19(21)20(15-25-13-5-2-6-14-25)22(24)16-26-18-11-9-17(23)10-12-18/h3-4,7-12H,2,5-6,13-16H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Affinity for human Neuropeptide Y receptor type 4				J Med Chem 40: 3712-4 (1997) Article DOI: 10.1021/jm970512x BindingDB Entry DOI: 10.7270/Q2HQ3Z1P
					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 5 (Homo sapiens (Human))	BDBM50060727 (2-(4-Chloro-phenoxymethyl)-1-methyl-3-piperidin-1-...) Show SMILES Cn1c(COc2ccc(Cl)cc2)c(CN2CCCCC2)c2ccccc12 Show InChI InChI=1S/C22H25ClN2O/c1-24-21-8-4-3-7-19(21)20(15-25-13-5-2-6-14-25)22(24)16-26-18-11-9-17(23)10-12-18/h3-4,7-12H,2,5-6,13-16H2,1H3	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Affinity for human Neuropeptide Y receptor type 5				J Med Chem 40: 3712-4 (1997) Article DOI: 10.1021/jm970512x BindingDB Entry DOI: 10.7270/Q2HQ3Z1P
					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 2 (Homo sapiens (Human))	BDBM50060727 (2-(4-Chloro-phenoxymethyl)-1-methyl-3-piperidin-1-...) Show SMILES Cn1c(COc2ccc(Cl)cc2)c(CN2CCCCC2)c2ccccc12 Show InChI InChI=1S/C22H25ClN2O/c1-24-21-8-4-3-7-19(21)20(15-25-13-5-2-6-14-25)22(24)16-26-18-11-9-17(23)10-12-18/h3-4,7-12H,2,5-6,13-16H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Affinity for human Neuropeptide Y receptor type 2				J Med Chem 40: 3712-4 (1997) Article DOI: 10.1021/jm970512x BindingDB Entry DOI: 10.7270/Q2HQ3Z1P
					More data for this Ligand-Target Pair