Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 505.3 BDBM50064070

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50064070 (6-Bromo-2-[3-(1-methyl-1H-benzoimidazol-2-ylmethox...) Show SMILES Cn1c(COc2cccc(c2)-c2cc(=O)c3cc(Br)cc(C(O)=O)c3o2)nc2ccccc12 Show InChI InChI=1S/C25H17BrN2O5/c1-28-20-8-3-2-7-19(20)27-23(28)13-32-16-6-4-5-14(9-16)22-12-21(29)17-10-15(26)11-18(25(30)31)24(17)33-22/h2-12H,13H2,1H3,(H,30,31)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	210	n/a	n/a	n/a	n/a	n/a
Vrije Universiteit Curated by ChEMBL					Assay Description In vitro affinity for CysLT1 receptors on guinea pig lung membranes, measured by displacement of [3H]-LTD4.				J Med Chem 41: 1428-38 (1998) Article DOI: 10.1021/jm970179x BindingDB Entry DOI: 10.7270/Q21835MZ
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