Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 388.3 BDBM50134623

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 8 (Homo sapiens (Human))	BDBM50134623 (CHEMBL3746140) Show SMILES Cn1c2nc(ncc2cc(Oc2ccc(F)cc2F)c1=O)N1CCCC(O)C1 Show InChI InChI=1S/C19H18F2N4O3/c1-24-17-11(9-22-19(23-17)25-6-2-3-13(26)10-25)7-16(18(24)27)28-15-5-4-12(20)8-14(15)21/h4-5,7-9,13,26H,2-3,6,10H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
Semmelweis University Curated by ChEMBL					Assay Description Inhibition of JNK1 (unknown origin)				Bioorg Med Chem Lett 26: 424-8 (2016) Article DOI: 10.1016/j.bmcl.2015.11.099 BindingDB Entry DOI: 10.7270/Q24T6M6J
					More data for this Ligand-Target Pair