Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 429.3 BDBM174880

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Acyl-CoA desaturase 1 (Rattus norvegicus (Rat))	BDBM174880 (US9102669, 68) Show SMILES Cn1cc(cn1)-c1ccc(nn1)N1CCC(CC1)N1CCc2c1cc(Cl)cc2Cl Show InChI InChI=1S/C21H22Cl2N6/c1-27-13-14(12-24-27)19-2-3-21(26-25-19)28-7-4-16(5-8-28)29-9-6-17-18(23)10-15(22)11-20(17)29/h2-3,10-13,16H,4-9H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	25
Janssen Pharmaceutica NV US Patent					Assay Description The SCD1 enzymatic assay was done in a volume of 50 μL using 10 μg of RLM (prepared as described above) in a 96-well polypropylene plate (e...				US Patent US9102669 (2015) BindingDB Entry DOI: 10.7270/Q2BC3X9V
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