Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Cytochrome P450 11B1, mitochondrial
(Homo sapiens (Human)) | BDBM279785
(US10035804, Example 56)Show SMILES Cn1cc(cn1)C(=O)N1CCC2(CN(C2)c2cncc(c2)N2C(=O)c3ccc(Cl)cc3C2(C)C)CC1 Show InChI InChI=1S/C27H29ClN6O2/c1-26(2)23-10-19(28)4-5-22(23)25(36)34(26)21-11-20(13-29-14-21)33-16-27(17-33)6-8-32(9-7-27)24(35)18-12-30-31(3)15-18/h4-5,10-15H,6-9,16-17H2,1-3H3 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | n/a | n/a | 18.8 | n/a | n/a | n/a | n/a |
Hoffman-La Roche Inc.
US Patent
| Assay Description
Herein we identified the use of the G-402 cell line as a host cell to ectopically express (transiently or stably) enzymes of the CYP11 family. Specif... |
US Patent US10035804 (2018)
BindingDB Entry DOI: 10.7270/Q2GT5Q6H |
More data for this
Ligand-Target Pair | |
Cytochrome P450 11B2, mitochondrial
(Homo sapiens (Human)) | BDBM279785
(US10035804, Example 56)Show SMILES Cn1cc(cn1)C(=O)N1CCC2(CN(C2)c2cncc(c2)N2C(=O)c3ccc(Cl)cc3C2(C)C)CC1 Show InChI InChI=1S/C27H29ClN6O2/c1-26(2)23-10-19(28)4-5-22(23)25(36)34(26)21-11-20(13-29-14-21)33-16-27(17-33)6-8-32(9-7-27)24(35)18-12-30-31(3)15-18/h4-5,10-15H,6-9,16-17H2,1-3H3 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | n/a | n/a | 0.00300 | n/a | n/a | n/a | n/a |
Hoffman-La Roche Inc.
US Patent
| Assay Description
Herein we identified the use of the G-402 cell line as a host cell to ectopically express (transiently or stably) enzymes of the CYP11 family. Specif... |
US Patent US10035804 (2018)
BindingDB Entry DOI: 10.7270/Q2GT5Q6H |
More data for this
Ligand-Target Pair | |