Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Lysosomal Pro-X carboxypeptidase
(Homo sapiens (Human)) | BDBM50361790
(CHEMBL1938526)Show SMILES Cn1cc(cn1)C(NC(=O)CCN1CCC(CC1)c1ccccc1)c1ccc(Cl)cc1 Show InChI InChI=1S/C25H29ClN4O/c1-29-18-22(17-27-29)25(21-7-9-23(26)10-8-21)28-24(31)13-16-30-14-11-20(12-15-30)19-5-3-2-4-6-19/h2-10,17-18,20,25H,11-16H2,1H3,(H,28,31) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of recombinant human PrCP using Mca-Ala-Pro-Lys(Dnp)-OH as substrate measured for 30 mins by continuous fluorometric assay |
Bioorg Med Chem Lett 22: 658-65 (2011)
Article DOI: 10.1016/j.bmcl.2011.10.060
BindingDB Entry DOI: 10.7270/Q2B56K50 |
More data for this
Ligand-Target Pair | |
Lysosomal Pro-X carboxypeptidase
(Mus musculus) | BDBM50361790
(CHEMBL1938526)Show SMILES Cn1cc(cn1)C(NC(=O)CCN1CCC(CC1)c1ccccc1)c1ccc(Cl)cc1 Show InChI InChI=1S/C25H29ClN4O/c1-29-18-22(17-27-29)25(21-7-9-23(26)10-8-21)28-24(31)13-16-30-14-11-20(12-15-30)19-5-3-2-4-6-19/h2-10,17-18,20,25H,11-16H2,1H3,(H,28,31) | Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 25 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of recombinant mouse PrCP using Mca-Ala-Pro-Lys(Dnp)-OH as substrate measured for 30 mins by continuous fluorometric assay |
Bioorg Med Chem Lett 22: 658-65 (2011)
Article DOI: 10.1016/j.bmcl.2011.10.060
BindingDB Entry DOI: 10.7270/Q2B56K50 |
More data for this
Ligand-Target Pair | |