Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Arachidonate 5-lipoxygenase-activating protein
(Homo sapiens (Human)) | BDBM165149
(US9067917, 184 | US9682971, 184)Show SMILES Cn1ccc(n1)-c1ccc(Cn2c(CC(C)(C)C(O)=O)nc3cc(OCc4ccc5ccccc5n4)ccc23)cc1 Show InChI InChI=1S/C33H31N5O3/c1-33(2,32(39)40)19-31-35-29-18-26(41-21-25-13-12-23-6-4-5-7-27(23)34-25)14-15-30(29)38(31)20-22-8-10-24(11-9-22)28-16-17-37(3)36-28/h4-18H,19-21H2,1-3H3,(H,39,40) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
Similars
| US Patent
| 150 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
JANSSEN PHARMACEUTICA NV
US Patent
| Assay Description
The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai... |
US Patent US9682971 (2017)
BindingDB Entry DOI: 10.7270/Q2P26W84 |
More data for this
Ligand-Target Pair | |
Arachidonate 5-lipoxygenase-activating protein
(Homo sapiens (Human)) | BDBM165149
(US9067917, 184 | US9682971, 184)Show SMILES Cn1ccc(n1)-c1ccc(Cn2c(CC(C)(C)C(O)=O)nc3cc(OCc4ccc5ccccc5n4)ccc23)cc1 Show InChI InChI=1S/C33H31N5O3/c1-33(2,32(39)40)19-31-35-29-18-26(41-21-25-13-12-23-6-4-5-7-27(23)34-25)14-15-30(29)38(31)20-22-8-10-24(11-9-22)28-16-17-37(3)36-28/h4-18H,19-21H2,1-3H3,(H,39,40) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| 150 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Pharmaceutica NV
US Patent
| Assay Description
The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai... |
US Patent US9067917 (2015)
BindingDB Entry DOI: 10.7270/Q24748M5 |
More data for this
Ligand-Target Pair | |