Found 2 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Mitogen-activated protein kinase kinase kinase 11
(Homo sapiens (Human)) | BDBM354765
(Preparation of 6-(4-hydroxyphenyl)-1-(1-methyl-1H-...)Show SMILES Cn1ccc2cc(ccc12)-n1c2nc(cnc2[nH]c1=O)-c1ccc(O)cc1 Show InChI InChI=1S/C20H15N5O2/c1-24-9-8-13-10-14(4-7-17(13)24)25-19-18(23-20(25)27)21-11-16(22-19)12-2-5-15(26)6-3-12/h2-11,26H,1H3,(H,21,23,27) | PDB
NCI pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Rochester; Board of Regents of the University of Nebraska
US Patent
| Assay Description 200 ng (130 nM) MLK3 (Dundee, DU8313) was incubated with 1 μM inactive MKK7b (Dundee, DU703) in the presence of 2 μM cold ATP (Km) and 0.5 ... |
US Patent US10485800 (2019)
BindingDB Entry DOI: 10.7270/Q22B91DW |
More data for this Ligand-Target Pair | |
Mitogen-activated protein kinase kinase kinase 11
(Homo sapiens (Human)) | BDBM354765
(Preparation of 6-(4-hydroxyphenyl)-1-(1-methyl-1H-...)Show SMILES Cn1ccc2cc(ccc12)-n1c2nc(cnc2[nH]c1=O)-c1ccc(O)cc1 Show InChI InChI=1S/C20H15N5O2/c1-24-9-8-13-10-14(4-7-17(13)24)25-19-18(23-20(25)27)21-11-16(22-19)12-2-5-15(26)6-3-12/h2-11,26H,1H3,(H,21,23,27) | PDB
NCI pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Rochester
US Patent
| Assay Description 200 ng (130 nM) MLK3 (Dundee, DU8313) was incubated with 1 μM inactive MKK7b (Dundee, DU703) in the presence of 2 μM cold ATP (Km) and 0.5 ... |
US Patent US9814704 (2017)
BindingDB Entry DOI: 10.7270/Q27H1MRN |
More data for this Ligand-Target Pair | |