Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 389.3 BDBM372573

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Voltage-dependent T-type calcium channel subunit alpha-1H (Homo sapiens (Human))	BDBM372573 (N-[2-(4-Cyano-3-fluoro-benzyl)-2H-[1,2,3]triazol-4...) Show SMILES Cn1ncc2ccc(CC(=O)Nc3cnn(Cc4ccc(C#N)c(F)c4)n3)cc12 Show InChI InChI=1S/C20H16FN7O/c1-27-18-7-13(2-5-16(18)10-23-27)8-20(29)25-19-11-24-28(26-19)12-14-3-4-15(9-22)17(21)6-14/h2-7,10-11H,8,12H2,1H3,(H,25,26,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
University of Alberta					Assay Description Stock solutions of test compounds are prepared to a concentration of 10 mM in DMSO. For the Cav3.2 assay, serial dilutions of the compounds are prepa...				J Med Chem 49: 1668-83 (2006) BindingDB Entry DOI: 10.7270/Q2794709
					More data for this Ligand-Target Pair