Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 413.4 BDBM621092

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM621092 ((R)-N-(6-(6-(1- (trifluoromethyl)cyclo- propyl)imi...) Show SMILES FC(F)(F)C1(CC1)c1ccc2ncc(-c3cccc(N[C@H]4CNCC44CC4)n3)n2c1 |r| Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	0.800	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Interleukin-1 receptor-associated kinase 4 (Homo sapiens (Human))	BDBM621092 ((R)-N-(6-(6-(1- (trifluoromethyl)cyclo- propyl)imi...) Show SMILES FC(F)(F)C1(CC1)c1ccc2ncc(-c3cccc(N[C@H]4CNCC44CC4)n3)n2c1 |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Interleukin-1 receptor-associated kinase 1 (Homo sapiens (Human))	BDBM621092 ((R)-N-(6-(6-(1- (trifluoromethyl)cyclo- propyl)imi...) Show SMILES FC(F)(F)C1(CC1)c1ccc2ncc(-c3cccc(N[C@H]4CNCC44CC4)n3)n2c1 |r| Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	92	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair