Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Calcitonin gene-related peptide type 1 receptor
(Homo sapiens (Human)) | BDBM50192558
((R)-4-(2-oxo-1,2-dihydropyrido[2,3-d]pyrimidin-3(4...)Show SMILES FC(F)(F)CN1c2ccccc2C(=N[C@@H](NC(=O)N2CCC(CC2)N2Cc3cccnc3NC2=O)C1=O)c1ccccc1 |c:13| Show InChI InChI=1S/C30H28F3N7O3/c31-30(32,33)18-40-23-11-5-4-10-22(23)24(19-7-2-1-3-8-19)35-26(27(40)41)37-28(42)38-15-12-21(13-16-38)39-17-20-9-6-14-34-25(20)36-29(39)43/h1-11,14,21,26H,12-13,15-18H2,(H,37,42)(H,34,36,43)/t26-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 295 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Displacement of [125I]CGRP from human recombinant CGRP receptor |
Bioorg Med Chem Lett 16: 5052-6 (2006)
Article DOI: 10.1016/j.bmcl.2006.07.044
BindingDB Entry DOI: 10.7270/Q29S1QNX |
More data for this
Ligand-Target Pair | |
Calcitonin gene-related peptide type 1 receptor
(Homo sapiens (Human)) | BDBM50192558
((R)-4-(2-oxo-1,2-dihydropyrido[2,3-d]pyrimidin-3(4...)Show SMILES FC(F)(F)CN1c2ccccc2C(=N[C@@H](NC(=O)N2CCC(CC2)N2Cc3cccnc3NC2=O)C1=O)c1ccccc1 |c:13| Show InChI InChI=1S/C30H28F3N7O3/c31-30(32,33)18-40-23-11-5-4-10-22(23)24(19-7-2-1-3-8-19)35-26(27(40)41)37-28(42)38-15-12-21(13-16-38)39-17-20-9-6-14-34-25(20)36-29(39)43/h1-11,14,21,26H,12-13,15-18H2,(H,37,42)(H,34,36,43)/t26-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 616 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Activity at CGRP receptor assessed as inhibition of CGRP-stimulated cAMP production |
Bioorg Med Chem Lett 16: 5052-6 (2006)
Article DOI: 10.1016/j.bmcl.2006.07.044
BindingDB Entry DOI: 10.7270/Q29S1QNX |
More data for this
Ligand-Target Pair | |