Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Leukotriene A-4 hydrolase
(Homo sapiens (Human)) | BDBM50511325
(CHEMBL4475844)Show SMILES FC(F)(F)Oc1ccc(CCNC(=O)Cc2ccc(Oc3ccccc3)cc2)cc1 Show InChI InChI=1S/C23H20F3NO3/c24-23(25,26)30-21-12-6-17(7-13-21)14-15-27-22(28)16-18-8-10-20(11-9-18)29-19-4-2-1-3-5-19/h1-13H,14-16H2,(H,27,28) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 260 | n/a | n/a | n/a | n/a | n/a | n/a |
Goethe University Frankfurt
Curated by ChEMBL
| Assay Description
Inhibition of (His)6 tagged human recombinant LTA4H expressed in Escherichia coli BL21(DE3) using non-fluorescent L-arginine-7-amino-4-methylcoumarin... |
ACS Med Chem Lett 11: 298-302 (2020)
Article DOI: 10.1021/acsmedchemlett.9b00330
BindingDB Entry DOI: 10.7270/Q2M3303Q |
More data for this
Ligand-Target Pair | |
Bifunctional epoxide hydrolase 2
(Homo sapiens (Human)) | BDBM50511325
(CHEMBL4475844)Show SMILES FC(F)(F)Oc1ccc(CCNC(=O)Cc2ccc(Oc3ccccc3)cc2)cc1 Show InChI InChI=1S/C23H20F3NO3/c24-23(25,26)30-21-12-6-17(7-13-21)14-15-27-22(28)16-18-8-10-20(11-9-18)29-19-4-2-1-3-5-19/h1-13H,14-16H2,(H,27,28) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 500 | n/a | n/a | n/a | n/a | n/a | n/a |
Goethe University Frankfurt
Curated by ChEMBL
| Assay Description
Inhibition of full length human soluble epoxide hydrolase (1 to 555 residues) expressed in Escherichia coli BL21(DE3) using non-fluorescent PHOME as ... |
ACS Med Chem Lett 11: 298-302 (2020)
Article DOI: 10.1021/acsmedchemlett.9b00330
BindingDB Entry DOI: 10.7270/Q2M3303Q |
More data for this
Ligand-Target Pair | |