Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 490.4 BDBM126716

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysosomal Pro-X carboxypeptidase (Homo sapiens (Human))	BDBM126716 (US8785634, 86) Show SMILES FC(F)(F)Oc1ccc(cc1)S(=O)(=O)N1CCC2(CC1)OC(c1ccccc21)c1ccccn1 Show InChI InChI=1S/C24H21F3N2O4S/c25-24(26,27)32-17-8-10-18(11-9-17)34(30,31)29-15-12-23(13-16-29)20-6-2-1-5-19(20)22(33-23)21-7-3-4-14-28-21/h1-11,14,22H,12-13,15-16H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	7.80	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp US Patent					Assay Description The potency of compounds of formula I against PrCP was determined by a fluorescence intensity kinetic assay measuring the IC50 values of PrCP inhibit...				US Patent US8785634 (2014) BindingDB Entry DOI: 10.7270/Q2HH6HRS
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