SMILES String Search

Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 392.3
BDBM50434167

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 7 hits in this display
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Prolyl endopeptidase FAP (Mus musculus (Mouse))	BDBM50434167 (CHEMBL2385302 \| US9346814, Cmpd No 8 Example 11) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	12	n/a	n/a	n/a	n/a	8.3	37
Universiteit Antwerp; Fox Chase Cancer Center US Patent					Assay Description Enzyme activities were determined kinetically in a final volume of 200 μl for 10 minutes at 37° C. by measuring the initial velocities of pNA ...				US Patent US9346814 (2016) BindingDB Entry DOI: 10.7270/Q2W37V6D
Universiteit Antwerp; Fox Chase Cancer Center US Patent					More data for this Ligand-Target Pair
Prolyl endopeptidase FAP (Mus musculus (Mouse))	BDBM50434167 (CHEMBL2385302 \| US9346814, Cmpd No 8 Example 11) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
University of Antwerp (UA) Curated by ChEMBL					Assay Description Inhibition of mouse recombinant FAP expressed in HEK293 cells using Ala-Pro-p-nitroanilide as substrate incubated for 15 mins prior to substrate addi...				ACS Med Chem Lett 4: 491-6 (2013) Article DOI: 10.1021/ml300410d BindingDB Entry DOI: 10.7270/Q2KP83J7
University of Antwerp (UA) Curated by ChEMBL					More data for this Ligand-Target Pair
Prolyl endopeptidase (Homo sapiens (Human))	BDBM50434167 (CHEMBL2385302 \| US9346814, Cmpd No 8 Example 11) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	710	n/a	n/a	n/a	n/a	n/a	n/a
University of Antwerp (UA) Curated by ChEMBL					Assay Description Inhibition of human recombinant PREP expressed in Escherichia coli using Z-Gly-Pro-p-nitroanilide as substrate incubated for 15 mins prior to substra...				ACS Med Chem Lett 4: 491-6 (2013) Article DOI: 10.1021/ml300410d BindingDB Entry DOI: 10.7270/Q2KP83J7
University of Antwerp (UA) Curated by ChEMBL					More data for this Ligand-Target Pair
Prolyl endopeptidase (Homo sapiens (Human))	BDBM50434167 (CHEMBL2385302 \| US9346814, Cmpd No 8 Example 11) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	710	n/a	n/a	n/a	n/a	8.3	37
Universiteit Antwerp; Fox Chase Cancer Center US Patent					Assay Description Enzyme activities were determined kinetically in a final volume of 200 μl for 10 minutes at 37° C. by measuring the initial velocities of pNA ...				US Patent US9346814 (2016) BindingDB Entry DOI: 10.7270/Q2W37V6D
Universiteit Antwerp; Fox Chase Cancer Center US Patent					More data for this Ligand-Target Pair
Dipeptidyl peptidase 9 (Homo sapiens (Human))	BDBM50434167 (CHEMBL2385302 \| US9346814, Cmpd No 8 Example 11) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	8.3	37
Universiteit Antwerp; Fox Chase Cancer Center US Patent					Assay Description Enzyme activities were determined kinetically in a final volume of 200 μl for 10 minutes at 37° C. by measuring the initial velocities of pNA ...				US Patent US9346814 (2016) BindingDB Entry DOI: 10.7270/Q2W37V6D
Universiteit Antwerp; Fox Chase Cancer Center US Patent					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50434167 (CHEMBL2385302 \| US9346814, Cmpd No 8 Example 11) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	8.3	37
Universiteit Antwerp; Fox Chase Cancer Center US Patent					Assay Description Enzyme activities were determined kinetically in a final volume of 200 μl for 10 minutes at 37° C. by measuring the initial velocities of pNA ...				US Patent US9346814 (2016) BindingDB Entry DOI: 10.7270/Q2W37V6D
Universiteit Antwerp; Fox Chase Cancer Center US Patent					More data for this Ligand-Target Pair
Dipeptidyl peptidase 2 (Homo sapiens (Human))	BDBM50434167 (CHEMBL2385302 \| US9346814, Cmpd No 8 Example 11) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	8.3	37
Universiteit Antwerp; Fox Chase Cancer Center US Patent					Assay Description Enzyme activities were determined kinetically in a final volume of 200 μl for 10 minutes at 37° C. by measuring the initial velocities of pNA ...				US Patent US9346814 (2016) BindingDB Entry DOI: 10.7270/Q2W37V6D
Universiteit Antwerp; Fox Chase Cancer Center US Patent					More data for this Ligand-Target Pair