Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 440.3 BDBM487897

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM487897 (1-(pyrazolo[1,5-a]pyridin-4-yl)- 5-(trifluoromethy...) Show SMILES FC(F)(F)c1c(cnn1-c1cccn2nccc12)C(=O)Nc1ccnc(c1)C(F)(F)F Show InChI InChI=1S/C18H10F6N6O/c19-17(20,21)14-8-10(3-5-25-14)28-16(31)11-9-27-30(15(11)18(22,23)24)13-2-1-7-29-12(13)4-6-26-29/h1-9H,(H,25,28,31)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	107	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description MALT1 protease activity was assessed in an in vitro assay using a tetrapeptide as substrate and full-length MALT1 protein (Strep-MALT1(1-824)-His) pu...				US Patent US10954214 (2021) BindingDB Entry DOI: 10.7270/Q2SX6HB1
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